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Placebo-controlled trials to date appear to be relatively reassuring in terms of the adverse effects of these drugs over and above the adverse effects of any intervention leading to weight loss (for example loss of lean mass) but their widespread use has been relatively short-lived, so it is likely that some adverse effects will emerge over time, Griffin added

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Kevin Marcaida, Pharma Analyst at GlobalData, comments, PD1 antagonists dominated the market, reigning as the best-selling drugs by mechanism of action with $38.9 billion in sales

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